BLOOMINGTON, Ind. -- OG Anunoby wasnt a factor when No.3 Indiana lost in overtime at IPFWThe sophomore played only 13 minutes, leaving because of an illness -- and leaving the Hoosiers (4-1) without one of their best, most relied on playmakers.I dont think any of us understood how sick he was, because he didnt even practice again until part of the time on Friday, Indiana coach Tom Crean said. But the bottom line is, we didnt have the right edge (against IPFW).On Sunday night, the Hoosiers had that edge, and they were led by a healthy Anunoby. He scored a career-high 21 points and had eight rebounds, leading the Hoosiers to an 85-52 victory over Mississippi Valley State.Anunoby scored 15 of his 21 points in the first half against the overmatched Delta Devils (0-8).Robert Johnson added 14 points for Indiana, which was without Justin Blackmon Jr. because of a left knee injury.Indianas largest lead of the basketball game was 35.The game doesnt change really that much (with Blackmon Jr. out). Everybody knows their job out there on the court, Johnson said. Its hard not to have James (Blackmon Jr.) out there, but we have key (players) that we go to. Everybody else just steps up.Twenty of Indianas baskets came by way of an assist. Josh Newkirk and Curtis Jones combined for 11 assists. The Hoosiers outscored the Delta Devils 34-20 in the paint, and 19-8 in second chance points. Mississippi Valley State shot 32 percent from the floor (21-65). Indiana took advantage of the Delta Devils misses, outrebounding Mississippi Valley State 48-26. Thomas Bryant led the Hoosiers with 11 rebounds.The Delta Devils were without their leading scorer, Marcus Romain.My guys continued to play hard. (Anunoby) did an outstanding job. I was shocked by how well he can shoot from the perimeter, and he has a strong game inside, Mississippi Valley State coach Andre Payne said. I know Indiana has a great program. So, when they stepped on the floor, they were going to bring their `A game because they were not going to let another upset happen.POLL IMPLICATIONS: Indiana will square off with a Top 10 team for the second time this season when the No. 5 North Carolina visits Bloomington on Wednesday night.CAUSE FOR CONCERN: Blackmon was hurt in the Hoosiers 68-71 overtime loss to IPFW. Crean said it is too early to tell if the junior guard will be ready to go for the showdown with the Tar Heels.A BUMPY ROAD: Mississippi Valley States first 14 games of the season are on the road. No.3 Indiana is the third Big Ten opponent the Delta Devils have visited so far this season. Mississippi Valley State also lost at Northwestern and at Michigan State.UP NEXT:Indiana: Hosts North Carolina on Wednesday night.Mississippi Valley State: At Gonzaga on Thursday night.China Jerseys For Sale . Thousands of fans at Mosaic Stadium will be cozying up to each other in an effort to stay warm in chilly temperatures and block the Prairie wind that locals say can knock your socks off. Jerseys For Sale Outlet . 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Friday was the first time either had discussed the health problems that stymied them in Rio de Janeiro and forced them to withdraw from the hard-court warmup at Cincinnati.For Williams, its a sore right shoulder that she revealed started bothering her almost immediately after her Wimbledon victory. She said she practiced for just two days before the Olympics and has spent little time on court since as she undergoes physical therapy.For Djokovic, its a sore left wrist that he revealed he hurt in Rio a few days before his first-round Olympic loss to Juan Martin del Potro, a player who knows plenty about how that injury hinders a rightys two-handed backhand.Im just hoping that Monday when the tournament starts Ill be able to get as close to the maximum of executing my backhand shot as possible, said Djokovic, who sounded a bit more optimistic than Williams on Friday.Williams acknowledged shed prefer to have played more coming into the Open -- shes had just three singles matches since Wimbledon -- and needs to practice more.Im just now starting to feel a little better, she said. Hopefully just every day I will keep going higher.It wasnt a physical problem that burdened Djokovic during his third-round Wimbledon loss to 41st-ranked Sam Querrey, he acknowledged. Asked that day if he was 100 percent healthy, the 12-time major champ replied: Not really. But its not the place and time to talk about it.On Friday, Djokovic conceded it was some other things that I was going through privately. He wouldnt elaborate other than to say that now everything is fine.Speaking of left wrist injuries, Rafael Nadal said his keeps getting better but still isnt 100 percent. Because the 14-time Grand Slam champ is a lefty, his issue is the forehand.When he first came back, he recalled, you try to find movements to avoid the pain. Now he can start to hit his normal forehand again, but it still needs time to feel that I am more confident in my wrist.Both Djokovic and Williams face a former Grand Slam semifinalist in the first round.dddddddddddd Williams opens her bid for a record-breaking 23rd major title against Ekaterina Makarova, whos coming off an Olympic doubles gold medal.The Russian made two straight major semis -- at the 2014 U.S. Open, losing to Williams 6-1, 6-3, and the 2015 Australian Open. With her ranking slipping to 36th, she just missed a seed at Flushing Meadows.Doing an interview shortly after the draw was set, Djokovic joked he wasnt mentally ready to see his bracket quite yet and wanted to wait until Im alone. What hell see is a meeting with Jerzy Janowicz, a 2013 Wimbledon semifinalist whos been ranked as high as 14th. After struggling in recent years and missing much of this season because of injuries, Janowicz is No. 228 in the world and used a protected ranking to get into the U.S. Open.Nadal is a potential semifinal opponent for Djokovic, the defending champ, while Andy Murray and Stan Wawrinka are in the other half of the bracket.Williams could face fourth-seeded Agnieszka Radwanska in the semis, which is also when she could potentially meet sister Venus. Australian Open champ Angelique Kerber and French Open winner Garbine Muguruza are on the other side of the draw.Earlier in the tournament, Williams could run into opponents who have eliminated her at past majors. In the third round, she could meet Ana Ivanovic, who beat her at the 2014 Australian Open. And in the fourth round, she could face Sam Stosur, who stunned her in the 2011 U.S. Open final.Del Potro, the 2009 U.S. Open champ, is ranked just 142nd after three left wrist surgeries. Last week, Steve Johnson, the highest-ranked U.S. mens player, questioned whether the U.S. Tennis Association should award del Potro the wild card hed need to get in because the Argentine could possibly defeat an American in the first round. That scenario wont occur -- del Petro meets countryman Diego Schwartzman in his opener. But the 19th-seeded Johnson could face the Olympic silver medalist in the second round.Between Wimbledon and the Rio Games, del Potro defeated three of the U.S. Opens top four seeds. ' ' '